Fig. 2.
CY-induced mobilization of HPCs in mixed chimeras.
Mixed chimeras in which both wild type and G-CSFR–deficient hematopoietic cells contributed to hematopoiesis were treated with saline or CY (n = 6 for each), and the number of CFCs in the bone marrow, blood, and spleen were quantified. The growth of colonies in the absence or presence of 1 mg/mL G418 was used to discriminate between wild type (G418-sensitive [G418S]) and G-CSFR–deficient (G418-resistant [G418R]) CFCs. Data represent the mean plus or minus SD.