Fig. 8.
Both 4 and PSGL-1 mediate eosinophil binding.
Eosinophils were preincubated with mAbs against either α4 (HP1.2) or PSGL-1 (PL-1) for 15 minutes before they were allowed to interact with the HUVEC under flow at 1.5 dynes/cm2. After a 2-minute interaction, the number of eosinophils that bound per high-power field was calculated. *P < .05; **P < .01; n = 3.