Fig. 5.
Effects of CrmA overexpression on the susceptibility of Jurkat cells to tumor-mediated apoptosis.
CrmA or control Neo-Jurkat cells were labeled with [3H]TdR and coincubated with tumor cells at a tumor-to-lymphocyte cell ratio of 40:1. As controls, these cells were treated with agonistic anti-Fas Ab (CH-11, 200 ng/mL) or VP-16 (20 μmol/L). Target cell death was determined at the indicated time points by measuring loss in 3H-labeled DNA. The error bars represent the SEM of 8 replicates.