Fig. 11.
![Fig. 11. Effects of overexpression of Bcl-2 in Jurkat cells on their susceptibility to tumor-mediated DNA degradation. / Bcl-2 or control Neo-transfected Jurkat cells were labeled with [3H]TdR and coincubated with tumor cells at a tumor-to-lymphocyte cell ratio of 40:1. As controls, these cells were treated with agonistic anti-Fas Ab (CH-11, 200 ng/mL) or VP-16 (20 μmol/L). Target cell apoptosis was determined at the indicated time points by measuring loss in 3H-labeled DNA in the JAM assay. The error bars represent the SEM of 8 replicates.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/95/6/10.1182_blood.v95.6.2015/6/bloo00630011x.jpeg?Expires=1735571747&Signature=IdJcPtvHcxHL3paMkCYJUP8iaE~yoxBZufcxKoo-4Hs0Ly0NYv3Pa7HSw-aWMIBQQWN03azIlw6YVHMFRFqRWxkCitpWtZAhKAXIzC5wP-O8hIbVmUBlLbfkYC4akO7McO6q26PAPl6~F57ivIAb2YwgsL55LYr4fXX5TrdjBkJLf059X3k4p8MvpjuSgg0b-H2ooOrQ9aMJcIRcJdjek3C7h03Ujj1uC4Sqij6iL0DA7ObHKKvaTH9f~TooJ97vf2C7CLhmCwdjWIepn1Uvw5s53RSwXedLeMxhFRSZ1vh1zHz2oCSEQw2rw-p3BKy-e43kVJxWK2KMePBNfTMCuQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effects of overexpression of Bcl-2 in Jurkat cells on their susceptibility to tumor-mediated DNA degradation.
Bcl-2 or control Neo-transfected Jurkat cells were labeled with [3H]TdR and coincubated with tumor cells at a tumor-to-lymphocyte cell ratio of 40:1. As controls, these cells were treated with agonistic anti-Fas Ab (CH-11, 200 ng/mL) or VP-16 (20 μmol/L). Target cell apoptosis was determined at the indicated time points by measuring loss in 3H-labeled DNA in the JAM assay. The error bars represent the SEM of 8 replicates.
