Fig. 4.
Clearance of 125I-TFPIC127 in mice.
(A) Mice were injected intravenously with 15 pmol of125I-TFPIC127 and plasma radioactivities were determined at the indicated times (<). Clearance of bacterial recombinant 125I-TFPI was conducted in the same manner (ο), as was clearance of 125I-TFPIC127co-administered with 50 mg/kg of 39-kd protein (A). (B) Twenty minutes after administration of 15 pmol of125I-TFPIC127 100 units of heparin were administered and plasma radioactivities were determined at the indicated times. Three or more mice were used in each group.