Role of T cell subsets and E-T ratio in the cytotoxic effect.

(A) ⁵¹Cr-release assay with isolated primary human CD8+ and CD4+ T cells against cell line Blin-1 at different concentrations of bscCD19 × CD3 (E-T ratio 20:1; incubation time 4 hours). (B)⁵¹Cr-release assay with unstimulated primary human PBLs against CD19+ cell line Blin-1, with titration of bscCD19 × CD3 at different E-T ratios and incubation time of 4 hours.