PCR amplification patterns for critical markers in case 24.

Marker names indicated on the top of the figure are shown in order from telomere (left) to centromere (right). PCR analysis is shown for DNA isolated from normal buccal smear (B) compared with DNA from leukemia cells (L) isolated from the patient's bone marrow sample. For each marker, the 2 alleles in the buccal DNA are indicated by arrows. Markers D5S500 and D5S594 show retention of both alleles in the leukemia sample, whereas loss of 1 allele is apparent for markers D5S476 and D5S1372.