Fig. 1.
Fig. 1. β1 integrin signaling inhibits AICD in Jurkat cells. / Jurkat cells were stimulated with or without 50 μg/mL of immobilized anti-CD3 antibody for 24 hours in the presence or absence of 50 μg/mL of immobilized anti-β1 or IgG control antibodies. Apoptosis was determined by DNA fragmentation analysis as described in “Materials and methods.” The results are mean of 3 independent experiments, each done in a duplicate. *P < .05 between anti-CD3-stimulated control and anti-β1 antibody samples.

β1 integrin signaling inhibits AICD in Jurkat cells.

Jurkat cells were stimulated with or without 50 μg/mL of immobilized anti-CD3 antibody for 24 hours in the presence or absence of 50 μg/mL of immobilized anti-β1 or IgG control antibodies. Apoptosis was determined by DNA fragmentation analysis as described in “Materials and methods.” The results are mean of 3 independent experiments, each done in a duplicate. *P < .05 between anti-CD3-stimulated control and anti-β1 antibody samples.

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