Fig. 5.
Fig. 5. Engagement of the 2β1 integrin does not inhibit cycloheximide- or Fas-induced apoptosis in Jurkat cells. / Jurkat cells were stimulated with 20 μg/mL of cycloheximide for 6 hours (A) or with 1 μg/mL of anti-Fas antibody CH-11 for 24 hours (B) in the presence or absence of 50 μg/mL of collagen I or poly-l-lysine, or 50 μg/mL of immobilized activating anti-α2β1 antibody JSB2 or control antibodies. Apoptosis was determined by DNA fragmentation as previously described.

Engagement of the 2β1 integrin does not inhibit cycloheximide- or Fas-induced apoptosis in Jurkat cells.

Jurkat cells were stimulated with 20 μg/mL of cycloheximide for 6 hours (A) or with 1 μg/mL of anti-Fas antibody CH-11 for 24 hours (B) in the presence or absence of 50 μg/mL of collagen I or poly-l-lysine, or 50 μg/mL of immobilized activating anti-α2β1 antibody JSB2 or control antibodies. Apoptosis was determined by DNA fragmentation as previously described.

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