Fig. 2.
Diagrammatic representations of ATIC, ATIC-ALK, ALK, and NPM-ALK.
IMPCH, inosine monophosphate cyclohydrolase; AICARFT, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase; MB, NPM metal binding domain; TM, ALK transmembrane domain.