Structure of the GANP protein.

(A) Sections of spleens from SRBC-immunized and nonimmunized BALB/c mice were hybridized with the ganp antisense probe. The white pulp area (WP), red pulp area (RP), and GC area are indicated. (B) Deduced amino acid sequence of the ganp-encoded protein (sequence data available from the European Molecular Biology Laboratory; accession number AJ006590). (C) Schematic representation of the murine GANP protein. The region homologous to SAC3 and Map80, nuclear localization sequences (NLSs), and coiled-coil regions are indicated. The 4 LXXLL motifs are indicated by black.