Fig. 4.
Effect of granulocyte-macrophage colony-stimulating factor (GM-CSF) on activation of R4 region CD11bbright/CD11clow population during pulmonary adenoviral infection.
Following the procedure described in Figure 1, (A) MHC II and B7.1 expression was examined on R4 region for each group. Open histograms represent the background staining with the isotype control antibody, whereas solid histograms indicate staining with relevant monoclonal antibody against the indicated surface molecule. M1 markers represent the limit defining the expression at high levels of the corresponding marker. (B) The absolute cell numbers for double positive for CD11b and MHC II or B7.1 derived from a single mouse in different groups.