Effects of G-CSF on the percentages of CD4⁺cells secreting IFN-γ and IL-4.

Summary of the results obtained from 10 PBSC donors, including those exemplified in Figure 1. Bars represent percentages (mean ± SEM) in the IFN-γ and IL-4 expressing CD4⁺ cells before (black) and after (gray) treatment. Corresponding shifts in the mean fluorescence intensity for IFN-γ and IL-4 are described in the text. Statistical analysis (nonparametric Kruskal–Wallis test) for PHA: IL-4, P < .05; IFN-γ, P < .01. Statistical analysis for CD3 + IL-2: IL-4 P < .01; IFN-γP < .01.