Analysis of the breakpoint-containing clone g401.

Normal metaphase spreads were hybridized with the phage clone g401 (A). A repeat-free fragment derived from g401 (PP1) was hybridized to a somatic cell hybrid panel (B) and to tumor DNA (C). Arrow indicates the rearranged band in tumor DNA. Size markers are given in kbp. Tumor metaphase spreads were hybridized with a chromosome 1 PAC (PAC 35A12) that spanned the breakpoint (D).