Fig. 1.
Alignment of ALL patients' tumor-related VH1 and VH3 IgH sequences to illustrate design of consensus IgH probes.
Alignments show FRIII VH consensus regions to which TaqMan probes (reverse complement) are designed. (A) Alignment of 11 VH1 tumor-related IgH sequences showing consensus sequence of the VH1 TaqMan probe. (B) Alignment of 11 VH3 tumor-related sequences showing the sequences to which 2 VH3 TaqMan probes are designed.