Fig. 7.
Sequence of the der(1) and der(14) breakpoints aligned with Sγ4 and the normal sequence of chromosome 1.
Clone B109 was derived from cosmid S7D (Figure 3) and corresponds to the der(14) chromosome. Clone B10 is derived from cosmid S5A (Figure 3) and corresponds to the der(1) chromosome. P48-B5 is derived from the normal chromosome 1 P1. The switch gamma 4 sequence was obtained from GenBank. It is uncertain whether the minor differences between the switch gamma 4 sequence and the B10 sequence represent polymorphism, sequencing errors, or differences arising during the translocation.