Fig. 1.
Dose response to ATRA or 9-cis RA of mast cell growth supported by SCF.
The 1 × 104 10-week cultured mast cells were incubated in wells containing SCF at 100 ng/mL with either ATRA or 9-cis RA at 10−11 mol/L to 10−7 mol/L. After 2 weeks, the viable cells were enumerated. The results shown are from 1 representative experiment of 3. Similar results were obtained in the other 2 experiments. Significantly different from SCF alone (*P < .0005, **P < .0001).