Fig. 2.
The effects of study drug on the peripheral concentration of platelets in healthy human volunteers . Mean peripheral platelet counts are depicted by the solid circles for the 12 subjects receiving active drug (3 μg/kg PEG-rHuMGDF) by bolus subcutaneous injection. The results in the 4 individuals receiving placebo are indicated by the solid squares. The peripheral platelet count peaks at 522 ± 90 × 103/μL on day 12, and normalizes by day 28. No significant changes occur in the placebo group. Variance about the mean values is ± 1 SD.
