Fig. 4.
NK cells and T cells are significantly more effective at lysing PWM-treated myeloma tumor cell lines than untreated cells.
Untreated (A) or PWM-treated (B) myeloma tumor cell lines (MER, COL, RLO) were used as targets in 4-hour 51Cr release assays. Enriched NK (□) and T () cells were generated as described in “Materials and methods” and then used as effectors along with total PBMCs (▪). All effectors were cultured in the presence of IL-2 for at least 3 days prior to use. E:T ratios are 30:1. The data represent mean values ± SEM of 4 individual experiments. P< .05. *Indicates not significant.
