Fig. 6.
Rituximab can trigger ADCC of lymphoma lines.
The 51Cr-labeled cell lines were cultured at 5 × 104/mL in the presence of the indicated amounts of effector cells enriched for NK cells and in the presence (closed circles) or the absence (open circles) of 2 μg/mL rituximab. The cells were incubated for 4 hours at 37°C. 51Cr released in the supernatant was measured as percentage of total 51Cr released with 1% SDS. The results are the mean and SD of 3 independent experiments.