Fig. 2.
Results of treatment with 2 different doses of cyclophosphamide (CTX).
NOD/SCID mice given transplants of 10 × 106 Namalwa cells intraperitoneally were treated with either 150 mg/kg of body weight of CTX or 75 mg/kg of CTX on days 3, 5, and 7. When 150 mg/kg of CTX was administered (⧫, n = 10), 60% of the mice died of drug-related toxicity. When 75 mg/kg of CTX was given (▪, n = 10), none of the mice died of drug-related toxicity, and the delay in tumor growth was not significantly different than at the higher dose. The dotted line indicates tumor growth in 6 untreated controls (▴). Results are mean ± SD values for tumor volume.
