Fig. 4.
Treatment of bulky disease with CTX (75 mg/kg) or rituximab (25 mg/kg).
NOD/SCID mice (n = 4 per treatment group) that received transplants of 10 × 106 Namalwa cells intraperitoneally were treated on days 15, 17, and 20 after transplantation. CTX (▪) induced a significant but transient reduction in tumor burden, whereas rituximab (⧫) did not. The dotted line indicates tumor growth in untreated controls (▴). Results are mean ± SD values for tumor volume.
