Fig. 3.
Tax transactivates the Bcl-XL promoter through the NF-κB pathway in T cells.
Jurkat cells were transfected with HTLV-I Tax (Tax1), HTLV-II Tax (Tax2), M22, M47, or pCMV4 vector and (A) P1 Bcl2, (B) P2 Bcl2, (C) Pr Bcl-XL, (D) HTLV-LTR, or (E) NF-κB luciferase reporter constructs. Results are representative of 3 independent transfections.