Fig. 5.
FACS analyses of lymphocyte subsets in the unsorted and sorted T-cell fractions.
The proportional representation of CD4+ and CD8+ cells in the NIT+ T-cell fraction parallels the unsorted T-cell population after early and after late transduction. (A) The results after gene transfer on day 8 showed a proportional higher representation of CD4+ T cells in the cell populations, whereas in panel B, after gene transfer on day 23 of cultures, T cells consisted of 80% CD8+ cells and 20% CD4+ T lymphocytes.