Fig. 1.
![Fig. 1. [CD4XL/CD3]-induced lymphocyte apoptosis is blocked by soluble Fas or by anti-FasL mAb. / Soluble Fas (sFas: closed circles) or 4H9 (closed squares) was added at the indicated concentrations (μg/mL) to the cultures of CD4 cross-linked T cells plus anti-CD3 mAb ([CD4XL/CD3]: open square), and apoptosis was evaluated by annexin V binding. Apoptotic populations of CD4XL alone (open circle) and/or anti-CD3/CD28 mAbs (open triangle) are also indicated. Data represent mean ± SD of 3 experiments. *Significantly (P < .001) different from CD4XL/CD3 samples.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/96/1/10.1182_blood.v96.1.195/4/bloo01351001x.jpeg?Expires=1735584154&Signature=pADX9dvRg4Gh12kvb8bNK2rzvdzHQkxQi3UCRECsKqJRJ3lfLnlcaVD4dJ8WMMT7mMmO5vddfwyDgYn7NAy4r8p2mB1~514n62BJuDcKg5Hm-s860fuCCOuy0wQj8AQhR2nzKrGtq5sZfXixoapJe~~BUlq3C22EBf7lse6Ij0NUBdbn8x6FSiOASduLVoDc5YgBl35ENFU3Xa6IRLyo~8WdLHwcG724XjIJr-Krq2EphG2TjyuzWkVQG0nRWUwu5DuETolDnVCzrDgcTQdUidvSNs70WSphF9NlPTCzArXET1uED7t~kWFOgJTYDsOSxo748RKqVoWNj3G9s-zz-Q__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
[CD4XL/CD3]-induced lymphocyte apoptosis is blocked by soluble Fas or by anti-FasL mAb.
Soluble Fas (sFas: closed circles) or 4H9 (closed squares) was added at the indicated concentrations (μg/mL) to the cultures of CD4 cross-linked T cells plus anti-CD3 mAb ([CD4XL/CD3]: open square), and apoptosis was evaluated by annexin V binding. Apoptotic populations of CD4XL alone (open circle) and/or anti-CD3/CD28 mAbs (open triangle) are also indicated. Data represent mean ± SD of 3 experiments. *Significantly (P < .001) different from CD4XL/CD3 samples.
