Fig. 7.
![Fig. 7. Neutralizing antibodies to TNF and IFNγ block [CD4XL/CD3]-induced T-cell apoptosis. / CD4XL/CD3 treatment was performed in PBTs in the absence or presence of various concentrations of anti-IFNγ antibody (open circles) or anti-TNFα antibody (closed circles). Data obtained from the simultaneous addition of anti-IFNγ antibody (1.0 μg/mL) and anti-TNFα antibody (3.0 μg/mL) are indicated as open squares. Apoptosis was determined by annexin V labeling. Data represent 2 independent experiments.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/96/1/10.1182_blood.v96.1.195/4/bloo01351007x.jpeg?Expires=1735583350&Signature=BJwuK3I5MOQlZLDxfY0cubQrsCU6iXQFRlLAGgygwru76bS95-8p0nY5Wxm2QoL2qlRKx8ChgYB9JB7qiNm0lWg9L86La-It2tv3V-RR~nAU2OM8deYpkNhkGUnjgkPkULNhKJn83X~0dHlTCKLjvyaJ9gy88HW3c10t8~dgdMtFvrcUwvqTvfUATbsoF4L0cW3~fU4RfwQ6l1uGssm~y4Gm7RskIHczcQXHD8FB13gKoyj8s3ssn~4dNricEeYDY3QckU4v8YyvgcaMbjvkEu7xTY3~kIKhFZYPPqbIe2x38uT0PyTJaWNjFuWGKt5Y37IX508OcWAtRSbfUx8QsQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Neutralizing antibodies to TNF and IFNγ block [CD4XL/CD3]-induced T-cell apoptosis.
CD4XL/CD3 treatment was performed in PBTs in the absence or presence of various concentrations of anti-IFNγ antibody (open circles) or anti-TNFα antibody (closed circles). Data obtained from the simultaneous addition of anti-IFNγ antibody (1.0 μg/mL) and anti-TNFα antibody (3.0 μg/mL) are indicated as open squares. Apoptosis was determined by annexin V labeling. Data represent 2 independent experiments.
