Comparison of levels of MIP-1 in marrow plasma from controls and patients with different stages of MM

. MIP-1α levels were measured as described in “Materials and methods.” MIP-1α levels were significantly higher (P < .05) in the patients with active disease compared to patients with inactive disease, patients with stage I MM, or normal controls. The dashed horizontal line represents the upper limit for normals ± 2 SD (75 pg/mL). Levels above this value were considered to be significantly elevated. The horizontal bars represent the mean for each group. The vertical bars represent the SEM for each group. Because the values in the y-axis are in logarithm scale, MIP-1α levels of 0 pg/mL in each group do not appear on the graph.