Synergistic effect of SDF-1 and MDC on washed platelet aggregation.

(A) The synergistic effect of MDC and epinephrine (Epi) on platelet aggregation. At the first arrow, 1 μmol/L epinephrine was added, followed by 100 nmol/L MDC or SDF-1. (B) The synergistic effect of 100 nmol/L SDF-1 and 5 μmol/L 5HT. (C) Similarly, neither 100 nmol/L SDF-1 nor MDC induced platelet aggregation, but the 2 agonists added together induced full aggregation of washed platelets.