Fig. 1.
Interaction of the fibrinogen Thr312Ala and FXIII Val34Leu polymorphisms in relation to PE.
In subjects homozygous for Thr312, possession of Leu34 was associated with a relative protection from PE compared with those homozygous for Val34 (χ2, P = .002). However, in those possessing Ala312, the protective effect of Leu34 is lost (χ2, P = .95).