Analysis of hemopoietic progenitor FL content from 14.5- to 15-day FLs from Cx43-wt (empty squares and bars) and Cx43-KO (filled squares and bars).

The results represent 3 independent experiments in which Cx43-wt (n = 11 fetuses; median: 7) and Cx43-KO (n = 9 fetuses; median: 3) FL cells had been obtained and compared within every experiment. (A) Weekly CAFC content. Actual mean numbers for weeks 1 to 6 per Cx43-wt FL were, respectively, 13 738, 5523, 2648, 853, 359, and 205, and for Cx43-KO FL they were, respectively, 10 148, 3369, 2061, 591, 316, and 195. (B) Colony-forming-cell content. Actual mean numbers were 3745 CFU-GM per Cx43-wt FL and 2876 per Cx43-KO FL, and 2215 BFU-E per Cx43-wt FL and 1525 BFU-E per Cx43-KO FL. *P < .05, between progenitor content of Cx43-wt and Cx43-KO FL cells.