Initial storage iron and red blood cell volume expansion.

(A) Relationship between initial storage iron (mg) and red blood cell volume expansion (mL/kg) in patients undergoing aggressive phlebotomy, without erythropoietin therapy. Based on data from reference 32. Linear regression analysis (not shown) demonstrated no significant correlation (r = 0.06; P = .67). (B) Relationship between initial storage iron (mg) and red blood cell volume expansion (mL/kg) in patients undergoing aggressive phlebotomy, with erythropoietin therapy. Linear regression analysis demonstrated a significant correlation (r = 0.6; P = .02). Reprinted with permission.32