Erythropoietic response, as reflected in the bone marrow erythropoietic index, in 4 cohorts of autologous donors treated with placebo or escalating doses of erythropoietin therapy.

(U/kg, given for 6 doses over 3 weeks.) Erythropoietic response (mL/kg per day) was estimated for each treatment group, according to the formula: bone marrow erythropoietic index = [RBC expansion] + [baseline RBC production] = [baseline RBC production]. Based on data from Goodnough et al.16