Changes in peripheral blood T-cell and CD4⁺T-cell subsets during sequential cycles of chemotherapy, PBPC infusions, and after completion of therapy.

The absolute number of each subset was determined using flow cytometry as described in “Materials and methods.” Samples were obtained at the time of maximal hematologic recovery from the preceding cycle of chemotherapy. Shaded areas represent 95% confidence intervals for normal values as described in “Materials and methods.” Horizontal lines denote median values. The time points noted as 1 to 30 months represent time after completion of PBPC-supported chemotherapy. Patients received 1 to 3 PBPC cycles as detailed in Table 1. N values for each time point are shown in the Figure 1 legend.