Fig. 1.
The effect of IL-4, IL-10, and IL-13 on A23187-stimulated LTB4 synthesis.
(A) Time-course study. PMNs were incubated with 10 ng/mL of IL-4, 100 ng/mL of IL-10, or 100 ng/mL of IL-13 for various periods of time. A23187-stimulated LTB4 production was measured by RIA as described in “Materials and methods.” Data represent mean ± SEM (n = 4). *P < .05 versus control. (B) Dose-response study. PMNs were incubated with various concentrations of IL-4, IL-10, or IL-13 for 6 hours, and A23187-stimulated LTB4 production was assayed.
