Fig. 4.
Cellularity in the bone marrow, thymus, and spleen.
(A) Bone marrow (BM) from 2 femurs and 2 tibiae); (B) thymus (THY); and (C) spleen (SPL) from Cx43+/+ and Cx43−/− mice 9 days after treatment with 5-FU or saline. Three to 4 mice of each genotype received the indicated treatment, and animals were processed individually. The ratio of recovery calculated as described in Materials and methods is indicated in parenthesis. The level of statistical significance between the different experimental groups is indicated. The results shown are from 1 of 2 identical experiments. Mice were 5 weeks of age when treated with 5-FU.