Fig. 1.
Expression of CC chemokines in lung parenchyma, BAL fluid, and serum on day 7 postallogeneic BMT as assessed by ELISA.
B10.BR recipient mice were preconditioned with TBI (7.5 Gy, day −1) with or without Cy (120 mg/kg per day, days −3, −2) as indicated and given C57BL/6 BM without (BM) or with 15 × 106 spleen cells (BMS) on the day of BMT (day 0). Lung protein extracts were obtained after exsanguination and BAL. (A ) Expression of MCP-1, MIP-1α, and RANTES. (B) Expression of eotaxin, MIP-1β, and C10. Mean values ± SD are indicated for 12 mice per group pooled from 2 experiments (except for RANTES and MIP-1β, n = 6 per group). *P < .05 vs control unmanipulated B10.BR mice; > 106 means all samples measured off-scale in the assay.