DC permeabilization was induced selectively by adenine triphosphate nucleotide analogs.

Adenosine, cAMP, ADP, UTP, ATPγS, and ATP were analyzed for their ability to permeabilize DCs. DC suspensions containing 10 μmol/L ethidium bromide were incubated for 15 minutes at 37°C with different nucleotide analogs (all at 5 mmol/L). Data shown were not normalized. Results express the average of 3 experiments (mean ± SD).