Peripheral blood analysis of rescued GATA-1.05mice.

Blood samples were obtained from 5-week-old mice. While peripheral blood from a G1R line No. 782 mouse (A) contains normal red blood cells, the peripheral blood from G2R line No. 620 (B) and G3R line No. 390 (C) contains nucleated red blood cells. Reticulocytosis is evident in G2R (E) and G3R (F) but not in G1R (D). (G-I) Scanning electron microscopy of peripheral red blood cells. Anisocytosis is observed in G3R (I). Original magnifications in panels G, H, and I are × 10 000, × 2300, and × 4300, respectively.