Comparison of effects of kinase inhibitors on apoptosis-regulatory proteins in B-CLL.

B-CLLs were cultured for 2 days with or without (control) 0.1 μmol/L flavopiridol or 1 μmol/L UCN-01. Immunoblot data were quantified by scanning densitometry to obtain rough estimates of the relative amounts of proteins. Data are expressed as a percentage relative to untreated (control) B-CLLs after normalization for β-actin. Bars indicate mean.