Fig. 4.
IC50 values of dCF in the inhibition of cell viability in primary culture of leukemia and lymphoma cells in the presence of dAd or AraA.
Cells were cultured with various concentrations of dCF in the presence of 10 μmol/L dAd (A) or 1 μmol/L AraA (B) for 5 days. The concentrations that inhibited the viable cell number by 50% (IC50) were calculated. Open circle in M4 indicates an eosinophilic variant. In the case of acute lymphocytic leukemia (ALL), open and closed circles indicate L1 and L2 subtypes, respectively. Follicular and diffuse type non-Hodgkin lymphoma (NHL) are open and closed circles, respectively.
