Effects of dCF and AraA on the survival of nude mice inoculated with monocytic leukemia U937 cells.

Mice were inoculated intraperitoneally with 3 × 10⁶ U937 cells. Three days after the inoculation, the mice were treated with saline alone (solid line), 10 mg/kg of AraA (dotted line), 0.25 mg/kg of dCF (broken line), or AraA plus dCF (bold line) 3 times per week. Twenty-eight mice were used in each of the “saline alone” and “AraA plus dCF” groups, and 15 mice were used in each of the “AraA” and “dCF” groups. The survival time of mice treated with dCF plus AraA was prolonged more than that of mice treated with dCF alone (P = .0001, log-rank and Wilcoxon tests).