Fig. 2.
Activation of reporter gene expression in HRCHO5 cells by epolones.
Luciferase activities in HRCHO5 cells following stimulation with the indicated concentrations of the 3 epolones—CPX, pycnidione, and 8-methyl-pyridoxatin—for 18 hours under normoxic (20% oxygen) or hypoxic (1% oxygen) conditions. Luciferase activities were determined as described in Figure 1. Means ± SD of 3 independent experiments.