Fig. 2.
Fig. 2. Growth characteristics of the human CML cell lines resistant to STI571. / (A) Cell viability assessed by trypan blue exclusion of LAMA84, AR230, K562, and KCL22 sensitive (s) and resistant (r) clones cultured in the presence (+) or absence of 1 μmol/L STI571. (B) Caspase 3 activity in 105 cells after 3 days in culture without (0 μmol/L) or with (1 μmol/L) STI571. Results represent the mean ± SD of triplicate cultures.

Growth characteristics of the human CML cell lines resistant to STI571.

(A) Cell viability assessed by trypan blue exclusion of LAMA84, AR230, K562, and KCL22 sensitive (s) and resistant (r) clones cultured in the presence (+) or absence of 1 μmol/L STI571. (B) Caspase 3 activity in 105 cells after 3 days in culture without (0 μmol/L) or with (1 μmol/L) STI571. Results represent the mean ± SD of triplicate cultures.

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