Fig. 2.
Histamine and catalase reverse GR-induced NK-cell inhibition.
Histamine (10 μmol/L, ●), catalase (100 U/mL, ▪), or culture medium (○) were added to 105 enriched NK cells alone or admixed with 2 × 104 or 5 × 104 GR in microplates. The compounds were added at the onset of a 16-hour assay. The inset shows a dose-response experiment using histamine (μmol/L) and catalase (U/mL) at an NK cell/GR ratio of 1:1. All data are cell lysis percent ± SEM of sextuplicate determinations.