Fig. 6.
Enhanced CCR1 receptor signaling capacity of CD26/DPP IV–processed LD78β.
LD78α (♦), intact LD78β (▴), and truncated LD78β(3-70) (●) were compared for their ability to induce an increase in [Ca++]i in HOS cells transfected with (A) CCR1 or (B) CCR5. The results represent the mean increase plus or minus SEM in [Ca++]i in 3 or more independent experiments. The detection limit for a significant increase in [Ca++]i is indicated by the dashed lines.