Fig. 10.
Autologous mixed lymphocyte reaction (MLR) with primary ALL nontransduced (mock-transduced) cells, cells transduced with control pHR-CMV-EGFP (EGFP), or cells transduced with pHR-CD80 (CD80).
(A) Primary MLR. (B) Secondary MLR. (C) MLR performed in the presence of blocking antibody to CD80 or the fusion protein cytotoxic T-lymphocyte antigen 4–immunoglobulin.