Migration and reconstitution of the epidermal LC population after UV-C irradiation.

(A) Characterization and phenotype of LCs in ear epidermal cell suspensions of control recipient Ly 5.1 mice. (B) Induction of LC egress from the epidermis by UV-C irradiation. Ly 5.1 mice were exposed to short wavelength UV-C irradiation for the indicated times, and the epidermal LC population was analyzed after 24 hours. (C) Recovery of the epidermal LC population after UV-C irradiation. Ly 5.1 mice were exposed to UV-C irradiation for 30 minutes and analyzed at the indicated times. The percentage of MHC II⁺ LCs is indicated. These results are representative of 4 experiments with similar results.