Fig. 3.
HIV-1 gp120/160-induced HUVEC apoptosis is inhibited by anti-CXCR4 receptor antibody.
HUVEC grown in LSM were untreated (control) or treated with gp120 (100 ng/mL) or gp160 (100 ng/mL) for 10 hours in the presence of the CXCR4 neutralizing antibody 12G5 (6 μg/mL) or the class-matched control IgG (6 μg/mL). Cell samples were analyzed for apoptosis by nucleosome ELISA. cAb, control antibody. *P < .036; **P < .003.