Fig. 7.
Controls for lysis of BLKSV40 and TRAMP-C.
For syngeneic controls, 3 × 106 B6 effector cells were grown for 5 days with 1 × 106 irradiated Balb/c stimulator cells. For allogeneic controls, 3 × 106Balb/c effector cells were grown for 5 days with 1 × 106irradiated B6 stimulator cells. Lines represent the mean percentage specific lysis and standard deviations in chromium release assays performed in triplicate with E:T ratios of 50:1, 10:1, and 2:1. Cytotoxic activity of syngeneic and allogeneic T cells and the p117-139–specific T-cell line against WT1-positive BLKSV40 cells (A) and TRAMP-C cells (B).