Effect of intranasal allergen challenge on eosinophil levels in eotaxin-deficient mice.

Mice were subjected to the induction of allergic airway inflammation by repeated challenges with A fumigatus antigen (+) or saline (−) and the level of eosinophils was measured 18 hours after the last challenge. The level of eosinophils was quantitated in the (A) bronchoalveolar lavage fluid (BALF) and (B) Peyer's patches of wild-type (+/+) or eotaxin-deficient (−/−) mice. The results are expressed as mean ± SEM (n = 7).